Integrins and human reproduction

Clarification of scope for Human Reproduction and Molecular Human Reproduction†.

As judged by any sentinel marker, ESHRE houses the most successful journals in reproductive health and disease, namely,Human Reproduction Update,Human Reproduction andMolecular Human Reproduction (MHR). This position has been achieved by continual publication of only the highest quality articles and constant innovation. With the change in editorship of all three ESHRE journals in 2013, the oppo...

Folate and human reproduction.

The influence of folate nutritional status on various pregnancy outcomes has long been recognized. Studies conducted in the 1950s and 1960s led to the recognition of prenatal folic acid supplementation as a means to prevent pregnancy-induced megaloblastic anemia. In the 1990s, the utility of periconceptional folic acid supplementation and folic acid food fortification emerged when they were pro...

Integrins and human intestinal cell functions.

Integrins are a large family of cell-surface receptors involved in cell adhesion to the extracellular matrix. In epithelia, it is mainly the integrins belonging to the beta1 and beta4 classes that bind to basement membrane molecules such as the laminins and the type IV collagens. Beta1 and beta4 integrins regulate the assembly of adhesive junctions as well as the activation of various signaling...

Genomic Imprinting and Human Reproduction

Parthenogenesis and Human Assisted Reproduction

Parthenogenetic activation of human oocytes obtained from infertility treatments has gained new interest in recent years as an alternative approach to create embryos with no reproductive purpose for research in areas such as assisted reproduction technologies itself, somatic cell, and nuclear transfer experiments and for derivation of clinical grade pluripotent embryonic stem cells for regenera...